Sioux City, Iowa hotel's full service makes the difference. When your travels bring you to Sioux City, Iowa, our hotel's friendly staff shows you why our commitment to hospitality sets us apart. Situated conveniently off of I 29 at exit 147B, the Holiday Inn Sioux City hotel's location is close to the area's major businesses and attractions. . From the exhibits at the Lewis and Clark Interpretive Center to great sporting events and live entertainment at Tyson Event Center to the Sioux City Hard Rock Casino, or a show at the Historic Orpheum Theater, our city offers something enjoyable for everyone. Business travelers love our hotel's downtown Sioux City, Iowa address. We're near Mercy Medical Center, St Luke's Hospital, June E. Nylen Cancer Center, the Sioux City Convention Center, Cargill, Morningside College, Briar Cliff University and Western Iowa Tech Community College are nearby. We provide a Business Center and meeting rooms too. No matter what brings you here, our winning combination of amenities and services will make you feel welcome in Sioux City. Our hotel's free high speed, WiFi Internet access, Fitness Center and indoor pool will ensure comfort and convenience. We look forward to your visit!